Clinical experience with biologic treatment in resistant eosinophilic fasciitis
نویسندگان
چکیده
منابع مشابه
Eosinophilic fasciitis*
Eosinophilic fasciitis is a rare sclerodermiform syndrome of unknown etiology. It is characterized by the thickening of the muscular fascia and subcutaneous tissue, with a variable infiltration of eosinophils. Peripheral eosinophilia, poly or monoclonal hypergammaglobulinemia and increased erythrocyte sedimentation rate can be seen. Clinical features begin acutely, with local edema and a painfu...
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Eosinophilic fasciitis is clinically characterized by symmetrical scleroderma-like indurations of the skin with pain. The histological features are fascial inflammation with lymphocytes and eosinophils as well as thickened and fibrotic fascia. Lymphocytic infiltration and degeneration of the underlying muscle are rarely observed. We report a 69-year-old Japanese woman who presented with multipl...
متن کاملEosinophilic fasciitis in siblings.
3. Information on permissions/orders of reprints in rheumatology and related fields. Silverman featuring research articles on clinical subjects from scientists working is a monthly international serial edited by Earl D.
متن کاملInfliximab may be effective in the treatment of steroid-resistant eosinophilic fasciitis: report of three cases.
OBJECTIVE EF is a rare fibrosing disorder that may involve skin and internal organs. Current therapies include moderate- to high-dose glucocorticoids with or without use of immunosuppressives. METHODS We report three cases of steroid-resistant EF in clinical practice who were treated with 3 mg/kg every 8 weeks infliximab therapy. RESULTS All patients noticed an improvement in their symptoms...
متن کاملEosinophilic fasciitis: MRI evaluation.
We conducted repeat muscle MR imaging (figure) on a 46-yearold man with relapsing eosinophilic fasciitis that can be classified in a continuum around the so-called Shulman syndrome.1 The patient had a 6-month history of relapsing fever and pain and swelling of the lower limbs, which responded to a moderate dosage of corticosteroids but relapsed several times after tapering of corticosteroids. I...
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ژورنال
عنوان ژورنال: Medicine
سال: 2021
ISSN: 0025-7974,1536-5964
DOI: 10.1097/md.0000000000025359